Publikationen im NUM

Hammerschmidt SI, Thurm C, Bošnjak B, et al . Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination. Eur J Immunol. 2022; 52(2):      [DOI] 

Momsen Reincke S, et al . SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies. Science (New York, N.Y.). 2022;      [DOI] 

Layer E, Hoehl S, Widera M, Bojkova D, Westphal T, Gottschalk R, Boeddinghaus B, Schork J, Ciesek S, Goetsch U. SARS-CoV-2 screening strategies for returning international travellers: Evaluation of a rapid antigen test approach. International Journal of Infectious Diseases. 2022; 118126—131.      [DOI] 

Backhaus I, Hermsen D, Timm J, Boege F, Lübke N, Degode T, Göbels K, Dragano N. SARS-CoV-2 seroprevalence and determinants of infection in young adults: A population-based seroepidemiological study. Public Health. 2022;      [DOI] 

Arora P, et al . SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination. Cell Reports. 2022; 39110754.      [DOI] 

Bahmer T, Borzikowsky C, Lieb W, Horn A, Krist L, Fricke J, Scheibenbogen C, Rabe KF, Maetzler W, Maetzler C, Laudien M, Frank D, Ballhausen S, Hermes A, Miljukov O, Haeusler KG, Mokhtari NEE, Witzenrath M, Vehreschild JJ, Krefting D, Pape D, Montellano FA, Kohls M, Morbach C, Störk S, Reese J, Keil T, Heuschmann P, Krawczak M, Schreiber S, group N. Severity, predictors and clinical correlates of Post-COVID syndrome (PCS) in Germany: A prospective, multi-centre, population-based cohort study. EClinicalMedicine. 2022 Sep.; 51(101549):101549.      [DOI]  [Pubmed] 

Medenwald D, Brunner T, Christiansen H, et al . Shift of radiotherapy use during the first wave of the COVID-19 pandemic? An analysis of German inpatient data. Strahlenther Onkol. 2022; 198(4):334—345.      [DOI] 

Schug C, Geiser F, Hiebel N, Beschoner P, Jerg-Bretzke L, Albus C, Weidner K, Morawa E, Erim Y. Sick Leave and Intention to Quit the Job among Nursing Staff in German Hospitals during the COVID-19 Pandemic. International Journal of Environmental Research and Public Health. 2022 Feb.; 19(4):1947.      [DOI]      [Datei] 

Koll C, Hopff S, Meurers T, Lee C, Kohls M, Stellbrink C, Thibeault C, Reinke L, Steinbrecher S, Schreiber S, others . Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients. Sci Data. 2022; 9(1):776.      [DOI] 

Mayer M, Zellmer S, Zenk J, et al . Status quo after one year of COVID-19 pandemic in otolaryngological hospital-based departments and private practices in Germany. Eur Arch Otorhinolaryngol. 2022; 279(2):      [DOI] 

Hoven H, Dragano N, Angerer P, Apfelbacher C, Backhaus I, Hoffmann B, Icks A, Wilm S, Fangerau F, Söhner F. Striving for health equality: The importance of social determinants of health and ethical considerations in pandemic preparedness planning. International Journal of Public Health. 2022; 671604542.      [DOI] 

Peter L, et al . Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients. Molecular therapy. Methods & clinical development. 2022; 2552–73.      [DOI] 

Gruendner J, Deppenwiese N, Folz M, Köhler T, Kroll B, Prokosch H, Rosenau L, Rühle M, Scheidl M, Schüttler C, Sedlmayr B, Twrdik A, Kiel A, Majeed RW. The Architecture for a feasibility query portal for distributed COVID-19 Fast Healthcare Interoperability Resources (FHIR) patient data repositories: Design and Implementation Study. JMIR Medical Informatics. 2022 Mai; 10(5):e36709.      [DOI]  [Pubmed] 

Czypionka T, Iftekhar EN, Prainsack B, Priesemann V, Bauer S, Valdez AC, Cuschieri S, Glaab E, Grill E, Krutzinna J, Lionis C, Machado H, Martins C, Pavlakis GN, Perc M, Petelos E, Pickersgill M, Skupin A, Schernhammer E, Szczurek E, Tsiodras S, Willeit P, Wilmes P. The benefits, costs and feasibility of a low incidence COVID-19 strategy. The Lancet Regional Health-Europe. 2022; 13100294.      [DOI] 

Krasemann S, Haferkamp U, Pfefferle S, et al . The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2. Stem Cell Reports. 2022; 17307-320.      [DOI] 

Ackermann M, Tafforeau P, Wagner W, et al . The Bronchial Circulation in COVID-19 Pneumonia. Am J Respir Crit Care Med. 2022; 205121-125.      [DOI] 

Prokosch H, Bahls T, Bialke M, Eils J, Fegeler C, Gruendner J, Haarbrandt B, Hampf C, Hoffmann W, Hund H, Kampf M, Kapsner LA, Kasprzak P, Kohlbacher O, Krefting D, Mang JM, Marschollek M, Mate S, Müller A, Prasser F, Sass J, Semler S, Stenzhorn H, Thun S, Zenker S, Eils R. The COVID-19 Data Exchange Platform of the German university medicine. Stud. Health Technol. Inform.. 2022 Mai; 294674—678.

Schons M, Pilgram L, Reese J, Stecher M, Anton G, Appel KS, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Brechtel M, Brinkmann F, Brünn C, Dhillon C, Fiessler C, Geisler R, Hamelmann E, Hansch S, Hanses F, Hanß S, Herold S, Heyder R, Hofmann A, Hopff SM, Horn A, Jakob C, Jiru-Hillmann S, Keil T, Khodamoradi Y, Kohls M, Kraus M, Krefting D, Kunze S, Kurth F, Lieb W, Lippert LJ, Lorbeer R, Lorenz-Depiereux B, Maetzler C, Miljukov O, Nauck M, Pape D, Püntmann V, Reinke L, Römmele C, Rudolph S, Sass J, Schäfer C, Schaller J, Schattschneider M, Scheer C, Scherer M, Schmidt S, Schmidt J, Seibel K, Stahl D, Steinbeis F, Störk S, Tauchert M, Tebbe JJ, Thibeault C, Toepfner N, Ungethüm K, Vadasz I, Valentin H, Wiedmann S, Zoller T, Nagel E, Krawczak M, Kalle C, Illig T, Schreiber S, Witzenrath M, Heuschmann P, Vehreschild JJ, Group NR. The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics. Eur. J. Epidemiol.. 2022 Aug.; 37(8):849—870.      [DOI]  [Pubmed] 

Borusiak P, Mazheika Y, Bauer S, Haberlandt E, Krois I, Fricke C, Simon L, Beschoner P, Jerg-Bretzke L, Geiser F, Hiebel N, Weidner K, Albus C, Morawa E, Erim Y. The impact of the COVID-19 pandemic on pediatric developmental services: a cross-sectional study on overall burden and mental health status. Arch Public Health. 2022; 80(1):113.

Hannemann J, Abdalrahman A, Erim Y, Morawa E, Jerg-Bretzke L, Beschoner P, Geiser F, Hiebel N, Weidner K, Steudte-Schmiedgen S, Albus C. The impact of the COVID-19 pandemic on the mental health of medical staff considering the interplay of pandemic burden and psychosocial resources-A rapid systematic review. PLoS One. 2022; 17(2):e0264290.      [DOI] 

Schreiber A, Viemann D, Schöning J, Schloer S, Mecate Zambrano A, Brunotte ea. The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses. Cell Mol Life Sci. 2022; 7965.      [DOI] 

Wratil PR, Stern M, Priller A, et al . Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern. Nat Med. 2022;      [DOI] 

Kamp J, Neubert L, Ackermann M, et al . Time-Dependent Molecular Motifs of Pulmonary Fibrogenesis in COVID-19. Int J Mol Sci. 2022; 23      [DOI] 

Wulff A, Biermann P, Landesberger T, Baumgartl T, Schmidt C, Alhaji AY, Schick K, Waldstein P, Zhu Y, Krefting D, Scheithauer S, Marschollek M. Tracing COVID-19 Infection Chains Within Healthcare Institutions - Another Brick in the Wall Against SARS-CoV-2. Studies in health technology and informatics. 2022; 290699—703.      [DOI] 

Schug C, Erim Y, Geiser F, Hiebel N, Beschoner P, Jerg-Bretzke L, Albus C, Weidner K, Steudte-Schmiedgen S, Borho A, Lieb M, Morawa E. Vaccination willingness against COVID-19 among healthcare workers in Germany: Results from a University Medicine Network survey between November 2020 and January 2021. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2022 Jan.; 65(1):74—85.      [DOI]      [Datei] 

Struwe C, Golinski M, Grimm C, Dickel S, Grummich K, Nothacker M, Voigt-Radloff S, Meerpohl J, Moerer O. Vergleich und Bewertung internationaler Leitlinien zur Behandlung schwerer Verläufe von SARS-CoV-2-Infektionen. Dtsch Arztebl Int. 2022; 11923-30.      [DOI] 

Mayer K. Pandemic Disruptions and Transnational Care Relations: Towards Closing the “Care Gap” in International Relations Theories. In: Gephart, W, editors. In the Realm of Corona Normativities II. Verlag Vitorrio Klostermann; 2022.

Kades K, Scherer J, Zenk M, Kempf M, Maier-Hein K. Towards Real-World Federated Learning in Medical Image Analysis Using Kaapana. In: Lecture Notes in Computer Science. Springer Nature Switzerland; 2022. p. 130—140.      [DOI] 

Dickel S, Grimm C, Popp M, Struwe C, Sachkova A, Golinski M, Seeber C, Fichtner F, Heise D, Kranke P, Meissner W, Laudi S, Voigt-Radloff S, Meerpohl J, Moerer O, Group On Behalf Of The German CEOsys Study . A Nationwide Cross-Sectional Online Survey on the Treatment of COVID-19-ARDS: High Variance in Standard of Care in German ICUs. J Clin Med. 2021 Jul. 29; 10(15):3363.      [DOI] 

Grimm C, Dickel S, Sachkova A, Popp M, Golinksi M, Fichtner F, Kranke P, Seeber C, Laudi S, Voigt-Radloff S, Moerer O. Targeted Minimal Staff-to-Patient Ratios Are Unachievable - A Nationwide Survey in German ICUs During the COVID-19 Pandemic. Cureus. 2021 Jun. 19; 13(6):e15755.      [DOI] 

Holzmann-Littig C, Braunisch MC, Kranke P, Popp M, Seeber C, Fichtner F, Littig B, Carbajo-Lozoya J, Allwang C, Frank T, Meerpohl JJ, Haller B, Schmaderer C. COVID-19 Vaccination Acceptance and Hesitancy among Healthcare Workers in Germany. Vaccines (Basel). 2021 Jul. 12; 9(7):777.      [DOI] 

Demichev V, Tober-Lau P, Lemke O, Nazarenko T, Thibeault C, Whitwell H, Röhl A, Freiwald A, Szyrwiel L, Ludwig D, Helbig E, Stubbemann P, Lippert L, Klein S, Mittermaier M, Machleidt F, García CV, Ruwwe-Glösenkamp C, Lingscheid T, Stegemann MS, Enghard P, Uhrig A, Müller-Redetzky HC, Hippenstiel S, Witzenrath M, Suttorp N, Mülleder M, Sander LE, group P, Ralser M, Kurth F, Correia-Melo C, Aulakh S, Grüning N, Blyuss O, Vernardis S, White M, Messner C, Joannidis M, Sonnweber T, Pizzini A, Wohlfarter Y, Sahanic S, Hilbe R, Schaefer B, Wagner S, Bosquillon de Jarcy L, Pfeiffer M, Jürgens L, Denker S, Zickler D, Zelezniak A, Campbell A, Hayward C, Porteous D, Marioni R, Zoller H, Löffler-Ragg J, Keller M, Tancevski I, Timms J, Zaikin A, Ramharter M, Lilley K. A time-resolved proteomic and prognostic map of COVID-19. Cell Syst. 2021;12(8):780-794.e7. 2021.

Doehn J, Tabeling C, Biesen R, Saccomanno J, Madlung E, Pappe E, Gabriel F, Kurth F, Meisel C, Corman VM, Hanitsch LG, Treskatsch S, Heim K, Stegemann MS, Ruwwe-Glösenkamp C, Müller-Redetzky HC, Uhrig A, Somasundaram R, Spies C, Bernuth H, Hofmann J, Drosten C, Suttorp N, Witzenrath M, Sander LE, Hübner R. CD169/SIGLEC1 is expressed on circulating monocytes in COVID-19 and expression levels are associated with disease severity.. Infection.2021;49(4):757-762. 2021.

Lorenz-Depiereux B, Vehreschild JJ, Stecher M, Pilgram L, Witzenrath M, Pley C, Thibeault C, Schreiber S, Bahmer T, Fiedler-Lacombe L, Blumentritt A, Stahl M, Hoffmann W, Hanß S, Krefting D, Schäfer C, Nauck M, Schaller J, Hoffmann M, Kraus M, On Behalf Of The Napkon Study Group . Challenges for Ethics coordination in a large Cohort Network – experiences in the German National Pandemic Cohort Network NAPKON.. Kongress European Biobank Week 2021. 2021.

Mühlemann B, Thibeault C, Hillus D, Helbig E, Lippert L, Tober-Lau P, Schwarz T, Müller MA, group P, Witzenrath M, Suttorp N, Sander LE, Drosten C, Jones TC, Corman VM, Kurth F. Impact of dexamethasone on SARS-CoV-2 concentration kinetics and antibody response in hospitalized COVID-19 patients: results from a prospective observational study. Clin Microbiol Infect. 2021;27(10). 2021.      [DOI] 

Weiner J, Suwalski P, Holtgrewe M, Rakitko A, Thibeault C, Müller M, Patriki D, Quedenau C, Krüger U, Ilinsky V, Helbig E, Lippert L, Stubbemann P, Wang X, Karadeniz Z, Saccomanno J, Doehn J, Hübner R, Hinzmann B, Siemann S, Corman VM, Mühlemann B, Drosten C, Jones TC, Suttorp N, Witzenrath M, Hippenstiel S, Skurk C, Group P, Sander LE, Beule D, Landmesser U, Guettouche T, Kurth F, Heidecker B, Popov I, Balnis J, Jaitovich A, Real L, Macías J, Pineda J, Fernandez-Fuertes M, Salvo M, Blueher A, Jurisic S, Beer J, Rutishauser J, Wiggli B, Schmid H, Danninger K, Binder R, Arjun Arkal R, Fragiadakis G, Mick E, Comet C, Calfee C, Erle D, Hendrickson C, Kangelaris K, Krummel M, Woodruff P, Langelier C, Venkataramani U, García F, Zyla J, Alice B, Zemojtel T, Wolfgang P, Borodina T, Ripke S. Increased risk of severe clinical course of COVID-19 in carriers of HLA-C. 04:01. EClinicalMedicine.2021;40:101099. 2021.

Horn A, Krist L, Lieb W, Montellano F, Kohls M, Haas K, Gelbrich G, Bolay-Gehrig S, Morbach C, Reese J, Störk S, Fricke J, Zoller T, Triller P, Kretzler L, Rönnefarth M, Kalle C, Kurth F, Steinbeis F, Witzenrath M, Bahmer T, Hermes A, Krawczak M, Reinke L, Maetzler C, Franzenburg J, Vehreschild JJ, Schons M, Illig T, Anton G, Ungethüm K, Heuschmann P, Keil T, Schreiber S. Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP). Infection. 2021;49(6):1277-87. IF: 3.553. 2021.

Horn A, Krist L, Lieb W, Montellano F, Kohls M, Haas K, Gelbrich G, Bolay-Gehrig S, Morbach C, Reese J, Störk S, Fricke J, Zoller T, Schmidt S, Triller P, Kretzler L, Rönnefarth M, Kalle C, Willlich S, Kurth F, Steinbeis F, Witzenrath M, Bahmer T, Hermes A, Krawczak M, Reinke L, Maetzler C, Franzenburg J, Vehreschild JJ, Schons M, Illig T, Anton G, Ungethüm K, Heuschmann P, Keil T, Schreiber S, Schmidt S, Willich SN, Enderle J, Flinspach A, Finkenberg BC, Gehrig MT, Savaskan N. Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP).. Infection. 2021;49(6):1277-87. IF: 3.553. 2021.

Anton G, Kuehn-Steven A, Taucher MK, Bernemann I, Illig T. Quality management in times of COVID-19: Remote audits as tool to assess sample quality for NAPKON.. European Biobank Week 2021. 2021.

Wendisch D, Dietrich O, Mari T, Von Stillfried S, Ibarra I, Mittermaier M, Mache C, Chua R, Knoll R, Timm S, Brumhard S, Kramer T, Mothes R, Bülow R, Schulze J, Djudjaj S, Pott F, Kazmierski J, Radke J, Baßler S, Conrad B, Landthaler M, Wyler E, Horst D, Hippenstiel S, Hocke A, Heppner F, Uhrig A, García CV, Herold S, Elezkurtaj S, Thibeault C, Witzenrath M, Suttorp N, Drosten C, Goffinet C, Kurth F, Schultze JL, Radbruch H, Ochs M, Eils R, Müller-Redetzky HC, Hauser AE, Conrad C, Wolff T, Boor P, Sander LE, Zauber H, Hiller A, Pascual-Reguant A, Leipold A, Erhard F, Geffers R, Pergantis P, Aschenbrenner A, Sawitzki B,  DCOI(, Cochain C, Luecken M, Theis F, Selbach M, Saliba A, Machleidt F. SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.. Cell. 2021;184(26):6243-6261.e27.. 2021.

Nouailles G, Wyler E, Pennitz P, Postmus D, Vladimirova D, Kazmierski J, Pott F, Dietert K, Muelleder M, Farztdinov V, Obermayer B, Andreotti S, Sawitzki B, Drosten C, Sander LE, Suttorp N, Ralser M, Beule D, Gruber A, Goffinet C, Landthaler M, Trimpert J, Witzenrath M, Wienhold S, Hoefler T. Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19. Nat Commun.2021;12(1):4869. 2021.

Witzenrath M, Kuebler W. The CypA-netics of Ventilator-induced Lung Injury. Am J Respir Crit Care Med. 204(4):385-387. 2021.

Jansky M, Schade F, Rieder N, Lohrmann D, Gebel C, others . ‘It felt like a black hole, great uncertainty, but we have to take care for our patients’–Qualitative findings on the effects of the COVID-19 pandemic on specialist palliative home care. PLOS ONE. 2021; 16(12):e0260767.      [DOI] 

Schloesser K, Simon ST, Pauli B, others . “Saying goodbye all alone with no close support was difficult”- Dying during the COVID-19 pandemic: an online survey among bereaved relatives about end-of-life care for patients with or without SARS-CoV2 infection. BMC Health Serv Res. 2021; 21(998):      [DOI] 

Gebel C, Kloppenburg L, Jansky MK, Nauck F, Schade F, Weddin U. „Es waren Kreativität und Umdenken erforderlich.“ Auswirkungen der COVID-19 Pandemie auf die spezialisierte ambulante Palliativversorgung (SAPV). Eine bundesweite Onlinebefragung. Gesundheitswesen. 2021;      [DOI] 

Reichardt M, Moller Jensen P, Andersen Dahl V, et al . 3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography. Elife. 2021; 10e71359.      [DOI] 

Reichardt M, Moller Jensen P, Andersen Dahl V, Bjorholm Dahl A, Ackermann M, Shah H, Länger F, Werlein C, Kuehnel MP, Jonigk D, Salditt T. 3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography. eLife. 2021; 10e71359.      [DOI]      [Datei] 

Vesper N, et al . A Barcoded Flow Cytometric Assay to Explore the Antibody Responses Against SARS-CoV-2 Spike and Its Variants. Frontiers in immunology. 2021; 12      [DOI] 

Iftekhar EN, Priesemann V, Balling R, Bauer S, Beutels P, Valdez AC, Cuschieri S, Czypionla T, Dumpis U, Glaab E, Grill E, Hanson C, Hotulainen P, Klimek P, Kretzschmar M, Krüger T, Krutzinna J, Low N, Machado H, Martins C, McKee M, Mohr SB, Nassehi A, Perc M, Petelos E, Pickersgrill M, Prainsack B, Rocklöv J, Schernhammer E, Staines A, Szczurek E, Tsiodras S, Van Gucht S, Willeit P. A look into the future of the COVID-19 pandemic in Europe: an expert consultation. The Lancet Regional Health-Europe. 2021; 8100185.      [DOI] 

Wang Z, Cryar A, Lemke O, Ludwig D, Tober-Lau P, Helbig ea. A multiplex protein panel assay determines disease severity and is prognostic about outcome in COVID-19 patients. medRxiv. 2021;      [DOI]