Funding for Organo-Strat within the National University Medicine Research Network (NUM) ended on 31 December 2021. Some of the research work will be continued in various working groups. Publications are updated on an ongoing basis.

COVID-19 is a novel infectious disease that can affect other organ systems in addition to the respiratory tract, especially in severe cases. The extent and nature of this extra-pulmonary organ involvement has a direct influence on the individual clinical prognosis as well as on therapeutic strategies and options. Accordingly, the overarching goal of the "National Competence Network Organo-Strat" is to make a significant contribution to the understanding of COVID-19 and the multiple organ involvement associated with the disease and possible treatment options. In order to clarify these largely open and clinically highly relevant questions, a systematic, organ-specific stratification for COVID-19 is being established. "Organo-Strat" will use COVID-19 to establish a modular and flexible network structure that will be able to provide information on organ-specific stratification as soon as new pathogens emerge, in the sense of "pandemic preparedness". Organo-Strat will take on these important tasks as an integral part of the National University Medicine Research Network (NUM). The pooling of expertise from a wide range of disciplines within the NUM is as unique as it is necessary to cope with this and future pandemics.

Organo-Strat

About the network
weiterlesen
Publications
weiterlesen
Contact us
weiterlesen

Goals

Clarifying the direct or indirect involvement of central organ systems in COVID-19 is a particular challenge. "Organo-Strat" investigates this question using organoids and 3D cultures generated from human tissues or human adult stem cells. Four specific objectives are addressed.