The academic medical centers, which were previously only involved in the MII as networking partners (and therefore had not yet established their own DIC), as well as some non-academic hospitals, are setting up the corresponding IT infrastructures and research data repositories and implementing the associated governance structures, data utilisation processes and data utilisation policies. In order to be integrated into the National Research Data Infrastructure Germany, both the already established and the newly emerging DICs connect to the central German Portal for Medical Research Data (FDPG) in order to automatically provide metadata on their data sets, answer feasibility queries and accept applications for data utilisation projects. If the DICs data are approved for a data use project by the local Use and Access Committees, the DIC make the requested patient cohorts/data sets available in harmonised FHIR format both for federated evaluations and for central analyses (if the corresponding patient consent has been obtained).