Publications in the NUM

Yusuf KO, Chaplinskaya-Sobol I, Schoneberg A, Hanß S, Valentin H, Lorenz-Depiereux B, Hansch S, Fiedler K, Scherer M, Sikdar S, Miljukov O, Reese J, Wagner P, Bröhl I, Geisler R, Vehreschild JJ, Blaschke S, Bellinghausen C, Milovanovic M, Krefting D. Impact of clinical study implementation on data quality assessments - using contradictions within interdependent health data items as a pilot indicator. Stud. Health Technol. Inform.. 2023 Sep.; 307152—158.      [DOI] 

Pappe E, Hammerich R, Saccomanno J, Sgarbossa T, Pohrt A, Schmidt B, Grah C, Eisenmann S, Holland A, Eggeling S, Stanzel F, Witzenrath M, Hübner R. Impact of Coronavirus disease 2019 on hospital admissions, health status, and behavioral changes of patients with COPD. Chronic Obstr. Pulm. Dis.. 2023 Jul.; 10(3):211—223.      [DOI] 

Granai M, Warm V, Vogelsberg A, Milla J, Greif K, Vogel U, Bakchoul T, Rosenberger P, Quintanilla-Martinez L, Schürch C, Klingel K, Fend F, Bösmüller H. Impact of P-selectin-PSGL-1 Axis on Platelet-Endothelium-Leucocyte Interactions in Fatal COVID-19. Laboratory Investigation; a Journal of Technical Methods and Pathology. 2023 May; 100179.      [DOI]      [File] 

Liu Z, Hollmann C, Kalanidhi S, Grothey A, Keating S, Mena-Palomo I, Lamer S, Schlosser A, Kaiping A, Scheller C, Sotzny F, Horn A, Nürnberger C, Cejka V, Afshar B, Bahmer T, Schreiber S, Vehreschild JJ, Miljukov O, Schäfer C, Kretzler L, Keil T, Reese J, Eichner FA, Schmidbauer L, Heuschmann PU, Störk S, Morbach C, Riemekasten G, Beyersdorf N, Scheibenbogen C, Naviaux RK, Williams M, Ariza ME, Prusty BK. Increased circulating fibronectin, depletion of natural IgM and heightened EBV, HSV-1 reactivation in ME/CFS and long COVID. medRxiv. 2023 Jun.; Online ahead of print      [DOI]  [Pubmed] 

Lichtner G, Haese T, Brose S, Röhrig L, Lysyakova L, Rudolph S, Uebe M, Sass J, Bartschke A, Hillus D, Kurth F, Sander LE, Eckart F, Toepfner N, Berner R, Frey A, Dörr M, Vehreschild JJ, Kalle C, Thun S. Interoperable, domain-specific extensions for the German Corona Consensus (GECCO) COVID-19 research data set using an interdisciplinary, consensus-based workflow: Data set development study. JMIR Med. Inform.. 2023 Jul.; 11e45496.      [DOI]  [Pubmed] 

Azeke AT, Schädler J, Ondruschka B, Steurer S, Möbius D, Fitzek A. Minimally Invasive Tissue Sampling via Post Mortem Ultrasound: A Feasible Tool (Not Only) in Infectious Diseases-A Case Report. Diagnostics (Basel, Switzerland). 2023 Aug.; 13(16):2643.      [DOI]      [File] 

Kottlors J, Fervers P, Geißen S, Gertz R, Bremm J, Rinneburger M, Weisthoff M, Shahzad R, Maintz D, Persigehl T. Morphological appearance of the B.1.1.7 mutation of the novel coronavirus 2 (SARS-CoV-2) in chest CT. Quant Imaging Med Surg. 2023; 13(2):1058—70.

Heinrich F, Huter T, Mertens S, Lange P, Vering J, Heinemann A, Nörz DS, Hoffmann A, Aepfelbacher M, Ondruschka B, Krasemann S, Lütgehetmann M. New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany. Emerging Infectious Diseases. 2023 Mar.; 29(3):652—656.      [DOI] 

Hoffmann M, Wong LR, Arora P, Zhang L, Rocha C, Odle A, Nehlmeier I, Kempf A, Richter A, Halwe NJ, Schön J, Ulrich L, Hoffmann D, Beer M, Drosten C, Perlman S, Pöhlmann S. Omicron subvariant BA.5 efficiently infects lung cells. Nature communications. 2023; 14(1):3500.      [DOI] 

Shi Y, Strobl R, Apfelbacher C, Bahmer T, Geisler R, Heuschmann P, Horn A, Hoven H, Keil T, Krawczak M, Krist L, Lemhöfer C, Lieb W, Lorenz-Depiereux B, Mikolajczyk R, Montellano FA, Reese JP, Schreiber S, Skoetz N, Störk S, Vehreschild JJ, Witzenrath M, Grill E, NAPKON Study Group . Persistent symptoms and risk factors predicting prolonged time to symptom-free after SARS‑CoV‑2 infection: an analysis of the baseline examination of the German COVIDOM/NAPKON-POP cohort. Infection. 2023 May; 51(6):1679–1694.      [DOI]  [Pubmed] 

Winkelmann S, Korth A, Voss B, Nasr MA, Behrend N, Pudszuhn A, Hofmann VM, Schendzielorz P, Maetzler C, Hermes A, Borzikowsky C, Bahmer T, Lieb W, Schreiber S, Störk S, Montellano FA, Witzenrath M, Keil T, Krawczak M, Laudien M, On Behalf Of The Napkon Study Group . Persisting chemosensory dysfunction in COVID-19 - a cross-sectional population-based survey. Rhinology. 2023 Feb.; 61(1):12—23.      [DOI] 

Fervers P, Fervers F, Rinneburger M, Weisthoff M, Kottlors J, Reimer R, Zopfs D, Celik E, Maintz D, Große-Hokamp N, Persigehl T. Physiological iodine uptake of the spine’s bone marrow in dual-energy computed tomography – using artificial intelligence to define reference values based on 678 CT examinations of 189 individuals. Front Endocrinol (Lausanne). 2023; 141365.

Surov A, Kardas H, Besutti G, Pellegrini M, Ottone M, Onur M, Atak F, Erdemir A, Hocaoglu E, Yıldız Ö, Inci E, Cingöz E, Cingöz M, Dursun M, Korkmaz İ, Orhan Ç, Strobel A, Wienke A, Pech M. Prognostic Role of the Pectoralis Musculature in Patients with COVID-19. A Multicenter Study. Acad Radiol. 2023; 30(1):77—82.      [DOI] 

Lutter M, Kniep I, Ondruschka B, Heinemann A. Pulmonale Befunde in der postmortalen Computertomographie bei COVID-19-assoziierten Todesfällen. Rechtsmedizin. 2023 Dec.; 3417—23.      [DOI]      [File] 

Ebong U, Büttner S, Schmidt S, Flack F, Korf P, Peters L, Grüner B, Stenger S, Stamminger T, Kestler H, Beer M, Kloth C. Quantitative Evaluation of COVID-19 Pneumonia CT Using AI Analysis—Feasibility and Differentiation from Other Common Pneumonia Forms. Diagnostics (Basel). 2023; 13(12):2129.      [DOI] 

Wolf D, Payer T, Lisson C, Lisson C, Beer M, Götz M, Ropinski T. Self-Supervised Pre-Training with Contrastive and Masked Autoencoder Methods for Dealing with Small Datasets in Deep Learning for Medical Imaging. Sci Rep. 2023; 1346433.

Thibeault C, Bardtke L, Vanshylla K, Cristanziano V, Eberhardt KA, Stubbemann P, Hillus D, Tober-Lau P, Mukherjee P, Münn F, Lippert LJ, Helbig ET, Lingscheid T, Steinbeis F, Mittermaier M, Witzenrath M, Zoller T, Group P, Klein F, Sander LE, Kurth F. Short- and long-term T cell and antibody responses following dexamethasone treatment in COVID-19. JCI Insight. 2023 Apr.; 8(8):      [DOI]  [Pubmed] 

Heyder R, Office NC, Group NS, Coordination N, Coordination R, Coordination A, Group GS. The German Network of University Medicine: technical and organizational approaches for research data platforms. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2023; 66(2):114—125.      [DOI] 

Miederer I, Rogasch JMM, Fischer R, Fuchs T, Lapa C, Lohmann P, Shi K, Tran-Gia J, Wendler T, Hellwig D. The Medical Informatics Initiative and the Network University Medicine - Perspectives for Nuclear Medicine. Nuklearmedizin. 2023; 62(5):276—283.      [DOI]  [Weblink] 

Lücke J, Nawrocki M, Schnell J, Meins N, Heinrich F, Zhang T, Bertram F, Sabihi M, Böttcher M, Blankenburg T, Pfaff M, Notz S, Kempski J, Reeh M, Wolter S, Mann O, Izbicki JR, Lütgehetmann M, Duprée A, Giannou AD, Ondruschka B, Huber S. TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver. Frontiers in Immunology. 2023; 141151937.      [DOI] 

Woo MS, Shafiq M, Fitzek A, Dottermusch M, Altmeppen H, Mohammadi B, Mayer C, Bal LC, Raich L, Matschke J, Krasemann S, Pfefferle S, Brehm TT, Lütgehetmann M, Schädler J, Addo MM, Wiesch J, Ondruschka B, Friese MA, Glatzel M. Vagus nerve inflammation contributes to dysautonomia in COVID-19. Acta Neuropathologica. 2023 Sep.; 146(3):387—394.      [DOI]      [File] 

Surov A, Thormann M, Kardas H, Hinnerichs M, Omari J, Cingöz E, Cingöz M, Dursun M, Kormaz İ, Orhan Ç, Yıldız Ö, Hocaoglu E, Inci E, Önder H, Erk H, Chousein O, Sasani H, Gönen K, Pech M, Wienke A. Visceral to subcutaneous fat ratio predicts short-term mortality in patients with Covid 19. A multicenter study. Br J Radiol. 2023; 96(1144):20220869.      [DOI] 

Mieling R, Neidhardt M, Latus S, Stapper C, Gerlach S, Kniep I, Heinemann A, Ondruschka B, Schlaefer A. Collaborative Robotic Biopsy with Trajectory Guidance and Needle Tip Force Feedback. In: 2023 IEEE International Conference on Robotics and Automation (ICRA). 2023 May. p. 6893—6900.      [DOI] 

Gallée L, Beer M, Götz M. Interpretable Medical Image Classification Using Prototype Learning and Privileged Information. In: Greenspan, Hayit and Madabhushi, Anant and Mousavi, Parvin and Salcudean, Septimiu and Duncan, James and Syeda-Mahmood, Tanveer and Taylor, Russell, editors. Medical Image Computing and Computer Assisted Intervention — MICCAI 2023. Cham: Springer Nature Switzerland; 2023. p. 435—445.      [DOI] 

Triefenbach L, Otto R, Bienzeisler J, Kombeiz A, Saskia E, Röhrig R, Majeed RW, Aktin Research Group . Establishing a data quality baseline in the AKTIN Emergency Department Data Registry – A secondary use perspective. Stud Health Technol Inform.. 2022 May 25; 294(25):209-213.      [DOI]  [Pubmed] 

Wang Z, Cryar A, Lemke O, Tober-Lau P, Ludwig D, Helbig E, Hippenstiel S, Sander L, Blake D, Lane C, others . A multiplex protein panel assay for severity prediction and outcome prognosis in patients with COVID-19: An observational multi-cohort study. EClinicalMedicine. 2022; 49101495.      [DOI] 

Demichev V, et al . A proteomic survival predictor for COVID-19 patients in intensive care. PLOS Digital Health. 2022; 1e0000007.      [DOI] 

Würstle S, Erber J, Hanselmann M, others . A telemedicine-guided self-collection approach for PCR-based SARS-CoV-2 testing: Comparative study. JMIR Formative Research. 2022; 6(1):      [DOI]      [File] 

Meng F, Kottlors J, Shahzad R, Liu H, Fervers P, Jin Y, Rinneburger M, Le D, Weisthoff M, Liu W, Ni M, Sun Y, An L, Huai X, Móré D, Giannakis A, Kaltenborn I, Bucher A, Maintz D, Zhang L, Thiele F, Li M, Perkuhn M, Zhang H, Persigehl T. AI support for accurate and fast radiological diagnosis of COVID-19: an international multicenter, multivendor CT study. Eur Radiol. 2022;      [DOI] 

Wygrecka M, Birnhuber A, Seeliger B, Michalick L, Pak O, Schultz A, Schramm F, Zacharias M, Gorkiewicz G, David S, Welte T, Schmidt J, Weissmann N, Schermuly R, Barreto G, Schaefer L, Markart P, Brack M, Hippenstiel S, Kurth F, Sander L, Witzenrath M, Kuebler W, Kwapiszewska G, Preissner K. Altered fibrin clot structure and dysregulated fibrinolysis contribute to thrombosis risk in severe COVID-19. Blood Adv. 2022; 6(3):1074—1087.      [DOI] 

Gagiannis D, Umathum VG, Bloch W, Rother C, Stahl M, Witte HM, Djudjaj S, Boor P, Steinestel K. Antemortem vs Postmortem Histopathologic and Ultrastructural Findings in Paired Transbronchial Biopsy Specimens and Lung Autopsy Samples From Three Patients With Confirmed SARS-CoV-2. American Journal of Clinical Pathology. 2022 Jan.; 157(1):54—63.      [DOI]      [File] 

Krasemann S, Dittmayer C, Stillfried S, Meinhardt J, Heinrich F, Hartmann K, Pfefferle S, Thies E, Manitius R, Aschman TAD, Radke J, Osterloh A, Schmid S, Buhl EM, Ihlow J, Dubois F, Arnhold V, Elezkurtaj S, Horst D, Hocke A, Timm S, Bachmann S, Corman V, Goebel H, Matschke J, Stanelle-Bertram S, Gabriel G, Seilhean D, Adle-Biassette H, Ondruschka B, Ochs M, Stenzel W, Heppner FL, Boor P, Radbruch H, Laue M, Glatzel M. Assessing and improving the validity of COVID-19 autopsy studies - A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses. EBioMedicine. 2022 Sep.; 83104193.      [DOI] 

Buhr L, Schicktanz S, Nordmeyer E. Attitudes Toward Mobile Apps for Pandemic Research Among Smartphone Users in Germany: National Survey. JMIR Mhealth Uhealth. 2022; 10(1):e31857.      [DOI] 

Schulz SR, et al . Augmented Neutralization of SARS-CoV-2 Omicron Variant by Boost Vaccination and Monoclonal Antibodies. European journal of immunology. 2022;      [DOI] 

Schmid B, Griesel M, Fischer A, Romero CS, Metzendorf M, Weibel S, Fichtner F. Awake Prone Positioning, High-Flow Nasal Oxygen and Non-Invasive Ventilation as Non-Invasive Respiratory Strategies in COVID-19 Acute Respiratory Failure: A Systematic Review and Meta-Analysis. J Clin Med. 2022; 11(2):391.      [DOI] 

Demleitner AF, Wolff A, Erber J, et al . Best practice approaches to outpatient management of people living with Parkinson's disease during the COVID-19 pandemic. J Neural Transm (Vienna). 2022; 129(11):1377-1385.      [DOI] 

Lingscheid T, Lippert L, Hillus D, Kruis T, Thibeault C, Helbig E, Tober-Lau P, Pfäfflin F, Müller-Redetzky H, Witzenrath M, Zoller T, Uhrig A, Opitz B, Suttorp N, Kramer T, Sander L, Stegemann M, Kurth F. Characterization of antimicrobial use and co-infections among hospitalized patients with COVID-19: a prospective observational cohort study. Infection. 2022; 50(6):1441—1452.      [DOI] 

Walker A, Houwaart T, Finzer P, Ehlkes L, Tyshaieva A, Damagnez M, Strelow D, Duplessis A, Nicolai J, Wienemann T, Tamayo T, Kohns Vasconcelos M, Hülse L, Hoffmann K, Lübke N, Hauka S, Andree M, Däumer MP, Thielen A, Kolbe-Busch S, Göbels K, Zotz R, Pfeffer K, Timm J, Dilthey AT. Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Clusters Based on Integrated Genomic Surveillance, Outbreak Analysis and Contact Tracing in an Urban Setting. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2022; 74(6):1039—1046.      [DOI] 

Schmidt M, Gebauer S, Bartholmes A, Kadioglu D, Kleesiek J, Hamm B, Vogl T, Penzkofer T, Bucher A, Storf H. CODEX Meets RACOON - A Concept for Collaborative Documentation of Clinical and Radiological COVID-19 Data. Stud Health Technol Inform. 2022;      [DOI] 

Dulovic A, et al . Comparative Magnitude and Persistence of Humoral SARS-CoV-2 Vaccination Responses in the Adult Population in Germany. Frontiers in Immunology. 2022; 13828053.      [DOI] 

Georg P, Astaburuaga-García R, Bonaguro L, Brumhard S, Michalick L, Lippert ea. Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Cell. 2022; 185493—512.e425.

Brandner J, Boor P, Borcherding L, et al . Contamination of personal protective equipment during COVID-19 autopsies. Virchows Arch. 2022; 1-10.      [DOI] 

Mardiko AA, Heinemann S, Bludau A, Kaba HEJ, Leha A, Maltzahn N, Mutters NT, Leistner R, Mattner F, Scheithauer S. COVID-19 vaccination strategy for hospital staff in Germany: a cross-sectional study in March-April 2021. The Journal of hospital infection. 2022; 12687—92.      [DOI] 

Scheithauer S, Bludau A, Heinemann S, Anton M, Knolle P. COVID-19-Impfstrategien für Beschäftigte deutscher Kliniken: Ergebnisse einer Befragung von Leitungen der (Krankenhaus\hbox-)Hygiene im Rahmen des B-FAST-Projektes. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2022; 65(12):1299—1306.      [DOI] 

Radbruch L, Bausewein C. Covid-19: Was die Palliativmedizin leisten kann. Rheinisches Ärzteblatt. 2022; (6):

Tober-Lau P, et al . Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections. Emerging infectious diseases. 2022; 28      [DOI] 

Meyer-Arndt L, et al . Cutting Edge: Serum but Not Mucosal Antibody Responses Are Associated with Pre-Existing SARS-CoV-2 Spike Cross-Reactive CD4+ T Cells following BNT162b2 Vaccination in the Elderly. Journal of immunology. 2022; 2081001–1005.      [DOI] 

Chen H, et al . Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel. EMBO Mol Med. 2022; 14e14182.      [DOI] 

Chen H, Maul‐Pavicic A, Holzer M, et al . Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel. EMBO Mol Med. 2022; 14(1):      [DOI]      [File] 

Tauchert M, Bernemann I, Kühn-Steven A, Kopfnagel V, Kunze S, Illig T, Anton G. Digital knowledge management within the NAPKON study. Abstract. 11. Nationales Biobanken Symposium. 2022. Not available. 2022;