Publications in the NUM

Vanshylla K, et al . Durability of omicron-neutralising serum activity after mRNA booster immunisation in older adults. The Lancet Infectious Diseases. 2022; 22445–446.      [DOI] 

Heinrich F, Romich C, Zimmermann T, Kniep I, Fitzek A, Steurer S, Glatzel M, Nörz D, Günther T, Czech-Sioli M, Fischer N, Grundhoff A, Lütgehetmann M, Ondruschka B. Dying of VOC-202012/01 — multimodal investigations in a death case of the SARS-CoV-2 variant. International Journal of Legal Medicine. 2022 Jan.; 136(1):193—202.      [DOI]      [File] 

Koerber N, Priller A, Yazici S, et al . Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents. Nat Commun. 2022; 13(1):      [DOI] 

Akbil B, et al . Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies. Journal of Clinical Immunology. 2022;      [DOI] 

Akbil B, Meyer T, Stubbemann P, Thibeault C, Staudacher O, Niemeyer D, Jansen J, Mühlemann B, Doehn J, Tabeling C, Nusshag C, Hirzel C, Sanchez DS, Nieters A, Lother A, Duerschmied D, Schallner N, Lieberum JN, August D, Rieg S, Falcone V, Hengel H, Kölsch U, Unterwalder N, Hübner R, Jones TC, Suttorp N, Drosten C, Warnatz K, Spinetti T, Schefold JC, Dörner T, Sander LE, Corman VM, Merle U, Group P, Kurth F, Bernuth H, Meisel C, Goffinet C. Early and rapid identification of COVID-19 patients with neutralizing type I interferon auto-antibodies. J. Clin. Immunol.. 2022 Aug.; 42(6):1111—1129.      [DOI]  [Pubmed] 

Pietzner M, Chua RL, Wheeler E, Jechow K, Radbruch H, Trump ea. ELF5 is a respiratory epithelial cell-specific risk gene for severe COVID-19. medRxiv. 2022;      [DOI] 

Hopff S, Tilch K, Kraus M, Lorenz-Depiereux L, Anton G, Appel K, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, others . Ethical and coordinative challenges in setting up a national cohort study exemplified by the German National Pandemic Cohort Network (NAPKON). Abstract ECCMID 2022. 2022;

Antoniou K, Vasarmidi E, Russell A, Andrejak C, Crestani B, Delcroix M, Dinh-Xuan A, Poletti V, Sverzellati N, Vitacca M, Witzenrath M, Tonia T, Spanevello A. European Respiratory Society statement on long COVID follow-up. Eur Respir J. 2022; 60(2):2102174.      [DOI] 

Krüger L, Klein J, Tobian F, others . Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2. Infection. 2022; 50      [DOI]      [File] 

Hoffmann M, et al . Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy. mBio. 2022;      [DOI] 

Hartung TJ, Neumann C, Bahmer T, Chaplinskaya-Sobol I, Endres M, Geritz J, Haeusler KG, Heuschmann PU, Hildesheim H, Hinz A, Hopff S, Horn A, Krawczak M, Krist L, Kudelka J, Lieb W, Maetzler C, Mehnert-Theuerkauf A, Montellano FA, Morbach C, Schmidt S, Schreiber S, Steigerwald F, Störk S, Maetzler W, Finke C. Fatigue and cognitive impairment after COVID-19: A prospective multicentre study. EClinicalMedicine. 2022 Nov.; 53(101651):101651.      [DOI]  [Pubmed] 

Ameratunga R, Woon S, Sheppard M, et al . First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity Reaction. J Clin Immunol. 2022;      [DOI] 

Von Stillfried S, Bülow R, Röhrig R, Boor P, Collaborators D. First report from the German COVID-19 autopsy registry. The Lancet Regional Health - Europe. 2022; 100330.      [DOI] 

Stillfried S, Bülow RD, Röhrig R, Boor P, COVID-19 Autopsies (DeRegCOVID) DC. First report from the German COVID-19 autopsy registry. The Lancet Regional Health. Europe. 2022 Apr.; 15100330.      [DOI] 

Steinbeis F, Knape P, Mittermaier M, Helbig E, Tober-Lau P, Thibeault C, Lippert L, Xiang W, Müller-Plathe M, Steinbrecher S, others . Functional limitations 12 months after SARS-CoV-2 infection correlate with initial disease severity: An observational study of cardiopulmonary exercise capacity testing in COVID-19 convalescents. Respir Med. 2022; 202106968.      [DOI] 

Rosenau L, Majeed RW, Ingenerf J, Kiel A, Kroll B, Köhler T, Prokosch H, Gruendner J. Generation of a Fast Healthcare Interoperability Resources (FHIR)-based Ontology for federated Feasibility Queries in the context of COVID-19: An automated approach. JMIR Med Inform. 2022 Apr.; 10(4):e35789.      [DOI] 

Kühnapfel A, Horn K, Klotz U, Kiehntopf M, Rosolowski M, Loeffler M, Ahnert P, Suttorp N, Witzenrath M, Scholz M. Genetic Regulation of Cytokine Response in Patients with Acute Community-Acquired Pneumonia. Genes (Basel). 2022; 13(1):111.      [DOI] 

Hirschbühl K, Schaller T, Märkl B, Claus R, Sipos E, Rentschler L, Maccagno A, Grosser B, Kling E, Neidig M, Kröncke T, Spring O, Braun G, Bösmüller H, Seidl M, Esposito I, Pablik J, Hilsenbeck J, Boor P, Beer M, Dintner S, Wylezich C. High viral loads: what drives fatal cases of COVID-19 in vaccinees? – an autopsy study. Modern Pathology. 2022 Aug.; 35(8):1013—1021.      [DOI]      [File] 

Dannebaum R, Suwalski P, Asgharian H, Du ZG, Lin H, Weiner J, Holtgrewe M, Thibeault C, Müller M, Wang X, others . Highly multiplexed immune repertoire sequencing links multiple lymphocyte classes with severity of response to COVID-19. EClinicalMedicine. 2022; 48101438.      [DOI] 

Hönzke K, Obermayer B, Mache C, Fathykova D, Kessler M, Dökel S, Wyler E, Baumgardt M, Löwa A, Hoffmann K, others . Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages. Eur Respir J. 2022; 60(6):2102725.      [DOI] 

Hönzke K, Obermayer B, Mache C, Fathykova D, Kessler M, Dökel ea. Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages. Eur Respir J. 2022; 60(6):2102725.      [DOI] 

Wolff AW, Haller B, Demleitner AF, Westenberg E, Lingor P. Impact of the COVID-19 pandemic on patients with Parkinson's Disease from the perspective of treating physicians-A nationwide cross-sectional study. Brain Sci.. 2022 Mar.; 12(3):353.

Bernatz S, Afat S, Othman AE, et al . Impact of the COVID-19 Pandemic on Radiology in Inpatient and Outpatient Care in Germany: A Nationwide Survey Regarding the First and Second Wave. Fortschr Röntgenstr. 2022; 19470-82.

Sedlmayr B, Sedlmayr M, Schüttler C, et al . Improving collaborative COVID-19 research of University Hospitals in Germany: Formative usability evaluation of the CODEX-Feasibility Portal. Appl Clin Inform. 2022; 13400—409.      [DOI] 

Wratil PR, Schmacke NA, Osterman A, et al . In-depth profiling of COVID-19 risk factors and preventive measures in healthcare workers. Infection. 2022; 50      [DOI] 

Dragano N, Reuter M, Peters A, Engels M, Schmidt B, Greiser K, Bohn B, Riedel-Heller S, Karch A, Mikolajczyk R, Krause G, Lang O, Panreck L, Rietschel M, Brenner H, Fischer B, Franzke C, Gastell S, Holleczek B, Jöckel K, Kaaks R, Keil T, Kluttig A, Kuß O, Legath N, Leitzmann M, Lieb W, Meinke-Franze C, Michels K, Obi N, Pischon T, Feinkohl I, Rospleszcz S, Schikowski T, Schulze M, Stang A, Völzke H, Willlich S, Wirkner K, Zeeb H, Ahrens W, Berger K. Increase in mental disorders during the COVID-19 pandemic - the role of occupational and financial strains. An analysis of the German National Cohort (NAKO) Study. Deutsches Ärzteblatt International. 2022; 119179–187.      [DOI] 

Bludau A, Heinemann S, Mardiko AA, Kaba HEJ, Leha A, Maltzahn N, Mutters NT, Leistner R, Mattner F, Scheithauer S. Infection control strategies for patients and accompanying persons during the COVID-19 pandemic in German hospitals: a cross-sectional study in March-April 2021. The Journal of hospital infection. 2022; 12528—36.      [DOI] 

Houwaart T, Belhaj S, Tawalbeh E, Nagels D, Fröhlich Y, Finzer P, Ciruela P, Sabrià A, Herrero M, Andrés C, Antón A, Benmoumene A, Asskali D, Haidar H, Dahlen J, Nicolai J, Stiller M, Blum J, Lange C, Adelmann C, Schroer B, Osmers U, Grice C, Kirfel PP, Jomaa H, Strelow D, Hülse L, Pigulla M, Kreuzer P, Tyshaieva A, Weber J, Wienemann T, Kohns Vasconcelos M, Hoffmann K, Lübke N, Hauka S, Andree M, Scholz CJ, Jazmati N, Göbels K, Zotz R, Pfeffer K, Timm J, Ehlkes L, Walker A, Dilthey AT. Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 2022; 27(43):      [DOI] 

Müller A, Haneke H, Kirchberger V, Mastella G, Dommasch M, Merle U, Heinze O, Siegmann A, Spinner C, Buiatti A, Laugwitz K, Schmidt G, Martens E. Integration of mobile sensors in a telemedicine hospital system: Remote-monitoring in COVID-19 patients. Journal of Public Health. 2022; 30(1):93—97.      [DOI] 

Kantauskaite M, et al . Intensity of mycophenolate mofetil treatment is associated with an impaired immune response to SARS-CoV-2 vaccination in kidney transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2022; 22634–639.      [DOI] 

Oorschot , others . Interaktive Homepage für Trauernde in Pandemiezeiten. Schmerz, Nervenarzt, Forum DKG, Urologe, Onkologe. 2022;

Dönges P, Wagner J, Contreras S, Iftekhar EN, Bauer S, Mohr SB, Dehning J, Valdez AC, Kretzschmar M, Mäs M, Nagel K, Priesemann V. Interplay Between Risk Perception, Behavior, and COVID-19 Spread. Frontiers in Physics. 2022; 10842180.      [DOI] 

Stillfried S, Bülow R, Röhrig R, Meybohm P, Boor P. Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report. Critical care (London, England). 2022; 2683.      [DOI] 

Stillfried S, Bülow RD, Röhrig R, Meybohm P, Boor P, COVID-19 Autopsies (DeRegCOVID) DC. Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report. Critical Care (London, England). 2022 Mar.; 26(1):83.      [DOI] 

Pauli B, Strupp J, Schloesser K, others . It’s like standing in front of a prison fence – Dying during the SARS-CoV2 pandemic: A qualitative study of bereaved relatives’ experiences. Palliative Medicine. 2022;      [DOI] 

Wyler E, Adler JM, Eschke K, Teixeira Alves G, Peidli S, Pott F, Kazmierski J, Michalick L, Kershaw O, Bushe J, Andreotti S, Pennitz P, Abdelgawad A, Postmus D, Goffinet C, Kreye J, Reincke SM, Prüss H, Blüthgen N, Gruber AD, Kuebler WM, Witzenrath M, Landthaler M, Nouailles G, Trimpert J. Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics. Mol. Ther.. 2022 May; 30(5):1952—1965.      [DOI]  [Pubmed] 

Fervers P, Kottlors J, Persigehl T, Lennartz S, Maus V, Fischer S, Styczen H, Deuschl C, Schlamann M, Mpotsaris A, Zubel S, Schroeter M, Maintz D, Fink G, Abdullayev N. Meaningful use of imaging resources to rule out cerebral venous sinus thrombosis after ChAdOx1 COVID-19 vaccination: Evaluation of the AHA diagnostic algorithm with a clinical cohort and a systematic data review. J Clin Neurosci. 2022;      [DOI] 

Krishnaratne S, Littlecott H, Sell K, Burns J, Rabe JE, Stratil JM, Litwin T, Kreutz C, Coenen M, Geffert K, Boger AH, Movsisyan A, Kratzer S, Klinger C, Wabnitz K, Strahwald B, Verboom B, Rehfuess E, Biallas RL, Jung-Sievers C, Voss S, Pfadenhauer LM. Measures implemented in the school setting to contain the COVID-19 pandemic: a rapid review. Cochrane Database of Systematic Reviews. 2022; 2022CD015029.      [DOI] 

Schwartz J, Reuters MC, Schallenburger M, Meier S, Roch C, Werner L, Oorschot B, Neukirchen M. Modelle guter Praxis: Alleine sterben ist ethisch nicht vertretbar. Praxis Palliative Care. 2022; 5429-36.

Wanner N, Andrieux G, Badia-i-Mompel P, et al . Molecular consequences of SARS-CoV-2 liver tropism. Nat Metab. 2022; 4310-319.      [DOI] 

Gruell H, et al . mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant. Nature Medicine. 2022;      [DOI] 

Liu Z, et al . Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19. Frontiers in immunology. 2022; 13838132.      [DOI] 

Bausewein C, Hodiamont F, Berges N, Ullrich A, Gerlach C, Oechsle K, Pauli B, Weber J, Stiel S, Schneider N, others . National strategy for palliative care of severely ill and dying people and their relatives in pandemics (PallPan) in Germany - study protocol of a mixed-methods project. BMC palliative care. 2022; 21(1):10.      [DOI] 

Heinrich F, Roedl K, Jarczak D, Goebels H, Heinemann A, Schäfer U, Ludwig F, Bachmann M, Bein B, Weber CF, Sydow K, Bota M, Paschen H, Weerth A, Veit C, Detsch O, Brand P, Kluge S, Ondruschka B, Wichmann D. New Insights in the Occurrence of Venous Thromboembolism in Critically Ill Patients with COVID-19-A Large Postmortem and Clinical Analysis. Viruses. 2022 Apr.; 14(4):811.      [DOI] 

Heinrich F, Roedl K, Jarczak D, et al . New Insights in the Occurrence of Venous Thromboembolism in Critically Ill Patients with COVID-19—A Large Postmortem and Clinical Analysis. Viruses. 2022; 14811.      [DOI] 

Arora P, et al . No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2. Cellular & Molecular Immunology. 2022;      [DOI] 

Ercanoglu MS, et al . No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults. iScience. 2022; 25103951.      [DOI] 

Zellmer S, Bachmann E, Muzalyova A, et al . One year of the COVID-19 pandemic in dental medical facilities in Germany: A questionnaire-based analysis. Int J Environ Res Public Health. 2022; 19(1):      [DOI] 

Jonigk D, Werlein C, Acker T, et al . Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?. Virchows Arch. 2022;      [DOI] 

Jonigk D, Werlein C, Acker T, Aepfelbacher M, Amann KU, Baretton G, Barth P, Bohle RM, Büttner A, Büttner R, Dettmeyer R, Eichhorn P, Elezkurtaj S, Esposito I, Evert K, Evert M, Fend F, Gaßler N, Gattenlöhner S, Glatzel M, Göbel H, Gradhand E, Hansen T, Hartmann A, Heinemann A, Heppner FL, Hilsenbeck J, Horst D, Kamp JC, Mall G, Märkl B, Ondruschka B, Pablik J, Pfefferle S, Quaas A, Radbruch H, Röcken C, Rosenwald A, Roth W, Rudelius M, Schirmacher P, Slotta-Huspenina J, Smith K, Sommer L, Stock K, Ströbel P, Strobl S, Titze U, Weirich G, Weis J, Werner M, Wickenhauser C, Wiech T, Wild P, Welte T, Stillfried S, Boor P. Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?. Virchows Archiv: An International Journal of Pathology. 2022 Aug.; 481(2):139—159.      [DOI]